Five-Year Survival 80 percent, up to 90 percent for those patients with surgically negative groin nodes
Investigational Same as Stage I.
Stage III
TNM T0-3, N0-1, M0
The tumor may be of any size with either adjacent spread to the vagina, urethra or anus or metastases to the groin lymph nodes on one side.
Standard Treatment Radical vulvectomy with groin lymph node dissection on both sides is the standard therapy. Sometimes, a pelvic lymph node dissection is done at the time of surgery if the groin lymph nodes are positive.
External beam radiation therapy is frequently given postoperatively to the groin and pelvis if there are groin lymph node metastases. With two or more pathologically positive groin nodes, there has been a significantly better survival rate with pelvic radiation than with pelvic lymph node dissection in a study conducted by the Gynecologic Oncology Group.
